Page 131 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 20 ฉบับที่ 1
P. 131
J Thai Trad Alt Med Vol. 20 No. 1 Jan-Apr 2022 111
Folin-Ciocalteu reagent revealed that the total induction are shown in Figure 1. The L. leu-
phenolic contents of L. leucocephala young cocephala extracts could significantly inhibit
leave extract was 325.6 ± 0.7 mg gallic acid the Heinz body formation of G6PD-deficient
equivalent/g of dry extract (mg GAE/g extract). human erythrocytes in a concentration-
dependent manner. The highest inhibition
2. Inhibition of Heinz body induction of Heinz bodies formation was about 12.8%
Levels of Heinz body formation in G6PD- at the concentration 1,000 μg/mL for G6PD
deficient erythrocytes were significantly deficient erythrocytes. Heinz body formation
higher than those in normal controls. The is often not recognized in normal erythrocytes
percentages of Heinz body formation by APH (Normal control).
A
Figure 1 Effect of young leaf extract from L. leucocephala on Heinz body formation by APH induction, showing:
(A) Heinz body formation was induced in erythrocytes and (B) Heinz body formation are represented
as mean ± SE, (*) significant differences at p < 0.05.
