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Journal of Thai Traditional & Alternative Medicine   Vol. 11 No. 1 January-April 2013  65



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                 Abstract
                     Comparative Efficacy of Sahasthara Capsule VS Diclofenac Tablet for the Relief of
                     Muscle Pain
                                  †
                                                     ‡
                     Preecha Nootim* , Waranee Bunchuailua , Nattiya Kapol ‡
                     *Research Institute of Thai Traditional Medicine, Department for Development of Thai Traditional and
                                     †
                     Alternative Medicine,  Master degree student in Consumer Protection in Public Health Program, Fac-
                                                                      ‡
                     ulty of Pharmacy, Silpakorn University, Nakhon Pathom province,  Department of Community Phar-
                     macy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom province
                     #+ Corresponding author: preecha.nootim@gmail.com
                         A double-blind randomized controlled trial was conducted to assess the efficacy of Sahasatara
                     capsule and diclofenac tablet for the treatment of muscle pain.  Subjects were males and females
                     aged 25-60 with muscle pain of the shoulder or neck who were outpatients at the Research Insti-
                     tute of Thai Traditional Medicine, Department for Development of Thai Traditional and Alterna-
                     tive Medicine, Ministry of Public Health.  Sixty-two subjects who met the inclusion and exclusion
                     criteria were equally randomized into two groups to receive one of the two following treatments:
                     Group 1, each subject was given one 400-mg Sahasatara capsule orally 3 times a day before meal
                     for 7 days; Group 2, each subject was given one 25-mg diclofenac capsule orally 3 times a day
                     after meal for 7 days.  The levels of pain as determined by patients using the Visual Analog Scale
                     on days 0 and 7 were compared within and between groups before and after the treatment. It was
                     found that the levels of pain on day 7 were significantly lower than the pre-treatment levels in
                     both groups, while the levels of pain either on day 0 or day 7 were not significantly different
                     between the two treatment groups. The results showed that the muscle pain-relieving effect of
                     Sahasatara at the dose of 1,200 mg/day was comparable to that of diclofenac at the dose of 75 mg/
                     day for 7 days.
                     Key words: Sahasathara, Diclofenac, Muscle Pain
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