Page 269 - วารสารการแพทย์แผนไทยและการแพทย์ ทางเลือก ปีที่ 19 ฉบับที่ 2 พฤษภาคม-สิงหาคม 2564

วารสารการแพทย์แผนไทยและการแพทย์ ทางเลือก Journal of Thai Traditional & Alternative Medicine
ปีที่ 19 ฉบับที่ 2 พฤษภาคม-สิงหาคม 2564 Vol. 19 No. 2 May-August 2021

รายงานเบื้องต้น

Preliminary Stability Study of Clinacanthus nutans

or Prayayor Cream

Nophadon Luangpirom
College of Allied Health Sciences, Suan Sunandha Rajabhat University, Dusit Sub-District, Dusit District, Bangkok 10300,
Thailand.
Corresponding author: nophadon.lu@ssru.ac.th

Abstract
This stability study of Clinacanthus nutans or Phayayor cream contained in the National List of Essential
Medicines B.E. 2561 (NLEM 2018) aimed to verify the appropriateness of the extraction and compounding methods.
It has been well known that it is impossible to incorporate the ethanolic extract into oil/water (o/w) cream base
since such a cream base will lose stability. So alcohol in the C. nutans ethanolic extract had to be removed or the
extract had to be modified so that it could be incorporated into the o/w cream base to avoid incompatibility. The
study suggests to emulsify the C. nutans extract with Tween 20 before incorporating it into the o/w cream base
to resolve the incompatibility problem. The study also emphasized the importance of assuring and promoting the
quality of Thai traditional medicines (e.g. Andrographis paniculata for treating pharyngotonsillitis, viral infections
and diarrhea, and Phayayor cream against herpes virus). Thai traditional medicines are not only used at the primary
care level, but also in the international market especially medical tourism as declared in the national Thai herbs
policy.
Key words: stability, Clincanthus nutans or Phayayor cream, preliminary study

Received date 17/05/21; Revised date 27/07/21; Accepted date 02/08/21

499