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«“√ “√°“√·æ∑¬å·ºπ‰∑¬·≈–°“√·æ∑¬å∑“߇≈◊Õ° ªï∑’Ë Û ©∫—∫∑’Ë Ò µÿ≈“§¡ ÚıÙ˜-¡°√“§¡ ÚıÙ¯ 87
nol is a potential Thai herbal extract to use for herbal health products. It has been reported
for several pharmacological uses such as hypotensive, immunostimulant, anti-fungal, anti-
inflammatory, and free radical scavenging activities. Since the quality of this extract has
not been reported yet. Therefore, a study was carried out using 9 samples of the 50 %
ethanolic extracts of crude drugs obtained from the Northern, Northeastern and Central
parts of Thailand. The values of water extractive, 50 % ethanol extractive, moisture
content and foaming index were given. Chemical identification of this extract both by
Thin-layer chromatography and High-performance liquid chromatography was also in-
cluded. The results of this study is beneficial for setting the preliminary criteria of chemi-
cal quality control of Thao-wan-priang extract in 50 % ethanol which will be useful for
quality control of its health products.
KEY WORDS : Thao-wan-priang extract in 50 % ethanol, Derris scandens (Roxb.)
Benth. extract in 50 % ethanol, chemical quality, quality control, health products.
∫∑π”
‡∂“«—≈¬å‡ª√’¬ß ¡’™◊ËÕ«‘∑¬“»“ µ√å«à“ Derris scandens (Roxb.) Benth. «ß»å Leguminosae-
(1)
Papilionoideae ™◊ËÕÕ—ß°ƒ… Jewel Vine ·≈–¡’™◊ËÕ∑âÕß∂‘ËπÕ◊ËπÊ ‡™à𠇧√◊Õ‡¢“Àπ—ß ‡∂“µ“ª≈“ ‡§√◊Õ
(1-2)
µ“ª≈“ æ“π‰ π ¬à“π‡À¡“– æ◊™™π‘¥π’ȇªìπ‰¡â‡∂“¢π“¥„À≠à „∫‡ªìπ„∫ª√–°Õ∫·∫∫¢ππ° „∫
(3)
¬àÕ¬√Ÿª√’ ™àÕ¥Õ°¬“« ’™¡æŸÕàÕπÀ√◊Õ ’¢“« ¡’°≈‘ËπÀÕ¡ÕàÕπÊ º≈‡ªìπΩí°·∫π‡≈Á° ¡’‡¡≈Á¥‡≈Á° „π
√√æ§ÿ≥¬“‰∑¬√–∫ÿ«à“„™â‡∂“‡ªì𬓷°â°√–…—¬ ·°â‡ âπ‡ÕÁπ¢Õ¥ ·°âª«¥‡¡◊ËÕ¬ ¢—∫ªí “«– ∫“ß·À≈àß
π‘¬¡π”≈”µâπ(‡∂“)À—Ë𵓰·Àâß§—Ë«‰ø ™ßπÈ”¥◊Ë¡·∑ππÈ”™“ „™â·°âª«¥‡¡◊ËÕ¬°≈â“¡‡π◊ÈÕ ∂â“„™â¥Õ߇À≈â“
(3-4)
®–‡ªìπ¬“¢—∫√–¥Ÿ à«π√“°„™â‡∫◊ËÕª≈“ (·µà‰¡à¡’§ÿ≥ ¡∫—µ‘¶à“·¡≈ß) πÕ°®“°π’È „π°“√»÷°…“∑“ß
‡¿ —™«‘∑¬“ ¡’√“¬ß“π«à“ “√ °—¥¥â«¬ 50 % ‡Õ∏“πÕ≈®“°≈”µâπ‡∂“«—≈¬å‡ª√’¬ß¡’ƒ∑∏‘Ï≈¥§«“¡¥—π‚≈À‘µ (5)
(6)
(7)
ƒ∑∏‘ϵâ“π‡™◊ÈÕ®ÿ≈‘π∑√’¬å ·≈–ƒ∑∏‘ϰ√–µÿâπ¿Ÿ¡‘§ÿâ¡°—π æ∫«à“ “√‡§¡’∑’Ë¡’ Ÿµ√‚§√ß √â“߇ªìπÕπÿæ—π∏å¢Õß
isoflavone ‰¥â·°à genistein 7-O-[α-rhamnosyl (1→6)]-β- glucosyl glycoside ¡’ƒ∑∏‘Ï
(8)
µâ“π°“√Õ—°‡ ∫ ·≈–ƒ∑∏‘ϵâ“πÕπÿ¡Ÿ≈Õ‘ √– à«πÕπÿæ—π∏å¢Õß isoprenyl ‰¥â·°à 3'γ,γ-
(9)
dimethylallylwighteone ·≈– scandenin ¡’ƒ∑∏‘Ï≈¥§«“¡¥—π‚≈À‘µ ·≈–ƒ∑∏‘ϵâ“π®ÿ≈‘π∑√’¬å „π
¢≥–∑’ËÕπÿæ—π∏å¢Õß isoflavone ·≈– benzil ¡’ƒ∑∏‘Ï≈¥§«“¡¥—π‚≈À‘µ ƒ∑∏‘ϵâ“πÕπÿ¡Ÿ≈Õ‘ √– ·≈–
ƒ∑∏‘ϵâ“π®ÿ≈‘π∑√’¬å πÕ°®“°π’Èæ∫«à“ “√‡§¡’°≈ÿà¡ dipenylisoflavone ‡™àπ 5,7,4′-trihydroxy-6,3′
(9)
(10)
-diprenylisoflavone ¡’ƒ∑∏‘χªì𬓵â“π‡™◊ÈÕ√“ Trichophyton mentagrophytes ¥â«¬ „π¢≥–∑’Ë
“√ °—¥®“°√“°‡∂“«—≈¬å‡ª√’¬ß æ∫«à“ “√‡§¡’°≈ÿà¡ diprenylisoflavone ‡™àπ warangalone, robustic