Page 88 - วารสารปีที่15ฉบับที่3

354

∫‘¥‡√◊ÈÕ√—ß ¡–μŸ¡∑—Èß 5 à«π (√“° ≈”μâπ „∫ ¥Õ° °“√»÷°…“π’È¡’«—μ∂ÿª√– ߧå‡æ◊ËÕ»÷°…“

·≈–º≈) ·°âª«¥»’√…– μ“≈“¬ ‡®√‘≠Õ“À“√ ≈¥ §ÿ≥ ¡∫—μ‘∑“߇§¡’·≈–°“¬¿“æ ´÷Ëߪ√–°Õ∫¥â«¬
[3]
§«“¡¥—π‚≈À‘μ Ÿß °“√æ‘ Ÿ®πå‡Õ°≈—°…≥å∑“߇§¡’ ª√‘¡“≥§«“¡™◊Èπ
“√‡§¡’∑’Ëæ∫„πº≈¡–μŸ¡ ‡™àπ marmelosin ª√‘¡“≥‡∂â“√«¡ ª√‘¡“≥‡∂â“∑’ˉ¡à≈–≈“¬„π°√¥
(imperatorin), luvangetin, aurapten, psoralen, ª√‘¡“≥ “√ °—¥¥â«¬‡Õ∑“πÕ≈ 95% ª√‘¡“≥ “√
marmelide, tannin ·≈–„π à«πÕ◊Ëπ Ê ¢Õß¡–μŸ¡ °—¥¥â«¬‡Õ∑“πÕ≈ 50% ·≈–ª√‘¡“≥ “√ °—¥¥â«¬πÈ”

‡™àπ „∫¡–μŸ¡ æ∫ “√ skimmianine, aeglin, ru- ´÷ËߢâÕ¡Ÿ≈∑’ˉ¥â®“°°“√»÷°…“π’È “¡“√∂𔉪®—¥∑”¢âÕ
tin, γ-sitosterol, β-sitosterol, flavone, lupeol, °”Àπ¥§ÿ≥¿“æ∑“߇§¡’¢Õߺ≈¡–μŸ¡ ‡æ◊ËÕª√–‚¬™πå

cineol, citral, glycoside, O-isopentenyl, „π°“√§«∫§ÿ¡§ÿ≥¿“æ«—μ∂ÿ¥‘∫ μ≈Õ¥®π°“√«‘®—¬
halfordiol, marmeline, citronellal, eugenol, ·≈–æ—≤π“μ”√—∫¬“∑’Ë¡’ à«πª√–°Õ∫¢Õߺ≈¡–μŸ¡
marmesinin, cuminaldehyde, phenylethyl μàÕ‰ª

cinnamamides ‡ª≈◊Õ°μâπ æ∫ “√ fagarine,
marmin πÈ”¡—πÀÕ¡√–‡À¬ æ∫ “√ D-limonene, A- √–‡∫’¬∫«‘∏’»÷°…“
D-phellandrene, cineol, citronellal, citral, p-
1. «— ¥ÿ
cymene, cumin aldehyde πÈ”¡—π®“°‡¡≈Á¥ æ∫ “√
palmitic acid, stearic acid, oleic acid, linoleic 1.1 μ—«Õ¬à“ߺ≈¡–μŸ¡
[4]
acid, linolenic acid °‘ËßÕàÕπ æ∫ “√ μ—«Õ¬à“ߺ≈¡–μŸ¡ ∑—Èßμ—«Õ¬à“ß ¥·≈–μ—«Õ¬à“ß
xanthotoxin, marmisin, scopoletin √“° æ∫ “√ ·Àâß ®”π«π 29 μ—«Õ¬à“ß √«∫√«¡®“°·À≈àßμà“ß Ê
aeglemarmelosina, skimmiamine, marmelosin, ∑—Èß·À≈àß∏√√¡™“μ‘·≈–√â“π ¡ÿπ‰æ√ ®”π«π 29
[5]
aurapten, epoxyaurapten, marmin ‡ªìπμâπ μ—«Õ¬à“ß „π√–À«à“߇¥◊Õπ¡‘∂ÿπ“¬π 2554 - ‡¡…“¬π
‚§√ß √â“ß∑“߇§¡’¢Õß “√‡§¡’∫“ß™π‘¥ · ¥ß„π√Ÿª∑’Ë 2556 π”º≈¡–μŸ¡ ¥ (º≈·°à·μଗ߉¡à ÿ°) ¡“≈â“ß„Àâ
1 –Õ“¥ Ω“π‡ªìπ·«àπ·≈⫺÷Ëß„Àâ·Àâß π”‰ªÕ∫„πμŸâÕ∫

O
O O O
O O O O

O O O

imperatorin (marmelos
marmelide
psoralen
imperatorin (marmelosin) psoralen marmelide
OCH 3
O O O
O
O O

luvangetin
aurapten
aurapten luvangetin
√Ÿª∑’Ë 1 Ÿμ√‚§√ß √â“ß∑“߇§¡’¢Õß “√ ”§—≠∫“ß™π‘¥∑’Ëæ∫„πº≈¡–μŸ¡