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®¨´„„µ¦Â¨³Á®˜»Ÿ¨ µ¦µ‡°¨ (barakol) Áž}œ­µ¦š¸É­„´—‹µ„ĝ ¸ÊÁ®¨È„ (Cassia siamea Lamk.) ‹µ„„µ¦«¹„¬µ

¡ªnµ µ¦µ‡°¨¤¸§š›·Í¨—‡ªµ¤—´œÃ¨®·˜Äœ®œ¼Â¦š Ž¹ÉŠ¤¸‡ªµ¤Áž}œÅžÅ—oªnµµ¦µ‡°¨‹³Åž„¦³˜»oœ
endothelium °Š®¨°—Á¨º°—Ä®o®¨´ÉŠ endothelium-derived relaxing factors (EDRF) šÎµÄ®o„¨oµ¤ÁœºÊ°Á¦¸¥

°Š®¨°—Á¨º°—‡¨µ¥˜´ªšÎµÄ®o‡ªµ¤—´œÃ¨®·˜¨—¨Š

ª´˜™»ž¦³­Š‡r Á¡ºÉ°«¹„¬µšµš„µ¦¥´¥´ÊŠ„µ¦®¨´ÉŠÅœ˜¦·„°°„ÅŽ—r °Š N-nitro-L-Arginine Methyl Ester (L-
NAME) ˜n°„µ¦°°„§š›·Í¨—‡ªµ¤—´œÃ¨®·˜ °Šµ¦µ‡°¨

ª´­—»Â¨³ª·›¸„µ¦ ­¨®œ¼Â¦š¡´œ›»rª·­˜µ¦r (Wistar) —oª¥ pentobarbital œµ— ÕÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤Ã—¥„µ¦

Œ¸—Á oµ®œoµšo°Š šÎµ tracheostomy Á¡ºÉ°Ážd—šµŠÁ—·œ®µ¥Ä‹Ä­n catheter š¸É®¨°—Á¨º°— common carotid artery
¨³ femoral vein Á¡ºÉ°´œš¹„‡ªµ¤—´œÃ¨®·˜°´˜¦µ„µ¦Á˜oœ °Š®´ªÄ‹ ¨³Ä®o­µ¦˜nµŠ Ç ®œ¼Â¦š„¨»n¤š¸É ÒÄ®o

µ¦µ‡°¨ œµ— Ò, Ô, Ö¨³ ÒÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤ šµŠ®¨°—Á¨º°——εÁ¡ºÉ°«¹„¬µ§š›·Í„µ¦¨—‡ªµ¤—´œÃ¨®·˜

(ؘ´ª) „¨»n¤š¸É ÓÄ®o L-NAME œµ— ÓÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤Áž}œÁª¨µ ÒÑ œµš¸ „n°œÄ®oµ¦µ‡°¨ œµ— Ò,

Ô, Ö¨³ ÒÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤Á¡ºÉ°«¹„¬µšµš„µ¦¥´¥´ÊŠÅœ˜¦·„°°„ÅŽ—r˜n°„µ¦°°„§š›·Í¨—‡ªµ¤—´œ
è®·˜ °Šµ¦µ‡°¨ (֘´ª) ´œš¹„„µ¦Áž¨¸É¥œÂž¨Š °Š‡ªµ¤—´œÃ¨®·˜Â¨³°´˜¦µ„µ¦Á˜oœ °Š®´ªÄ‹—oª¥

Á‡¦ºÉ°Š PowerLab

Ÿ¨„µ¦«¹„¬µ ¡ªnµµ¦µ‡°¨ œµ— Ò, Ô, Ö¨³ ÒÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤šÎµÄ®o‡ªµ¤—´œ systolic, diastolic

¨³°´˜¦µ„µ¦Á˜oœ °Š®´ªÄ‹¨—¨Š˜µ¤ œµ— °Šµ¦µ‡°¨ ×¥‡ªµ¤—´œ systolic ¨—¨Š ÒØ.×Õ% (p<Ñ.ÑÒ),
ÓÕ.ÕÙ% (p<0.01), ÓÕ.ÙÚ% (p<0.001) ¨³ ÔØ.ÒÑ% (p<0.05) ˜µ¤¨Îµ—´ ‡ªµ¤—´œ diastolic ¨—¨Š

ÓÑ.ÕÕ% (p<Ñ0.01), Ó×.ÕÕ% (p< 0.01), ÓÙ.ÖÚ% (p<0.001), ¨³ ÕØ% (p<Ñ0.05) ˜µ¤¨Îµ—´°´˜¦µ

„µ¦Á˜oœ °Š®´ªÄ‹¨—¨Š Ó.ÙÖ%, Ö.ÒÔ%, ÒÑ.ÕØ% ¨³ ÒÔ.Ø% ˜µ¤¨Îµ—´ Ĝ„¨»n¤š¸ÉÄ®o L-NAME œµ—
ÓÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤Áž}œÁª¨µ ÒÑ œµš¸ „n°œÄ®oµ¦µ‡°¨ œµ— Ò, Ô, Ö¨³ ÒÑ ¤·¨¨·„¦´¤/„·Ã¨„¦´¤

¡ªnµ‡ªµ¤—´œ systolic ¨—¨Š Ò.ÕÕ%, Ô.×Ú%, Ô.ÓÓ% ¨³ ÒÕ% ˜µ¤¨Îµ—´ ‡ªµ¤—´œ diastolic ¨—¨Š

Ó.×Ù%, Ô.Ô×%, Ò.×Ò%, ¨³ ÒÒ.Ø% ˜µ¤¨Îµ—´­nªœ°´˜¦µ„µ¦Á˜oœ °Š®´ªÄ‹¨—¨Š Ò.ØÓ%, Ñ.ÙÓ%,
Ñ.ÔÒ% ¨³ Ñ.×% ˜µ¤¨Îµ—´

o°­¦»ž µ¦µ‡°¨¤¸§š›·Í¨—‡ªµ¤—´œÃ¨®·˜ °Š®œ¼Â¦šš¸É¤¸‡ªµ¤—´œÃ¨®·˜ž„˜·°¥nµŠ¤¸œ´¥­Îµ‡´šµŠ­™·˜·Ž¹ÉŠ

Áž}œÅžÅ—oªnµ µ¦µ‡°¨‹³Åž„¦³˜»oœÄ®o¤¸„µ¦®¨´ÉŠÅœ˜¦·„°°„ÅŽ—r šÎµÄ®o„¨oµ¤ÁœºÊ°Á¦¸¥ °Š®¨°—Á¨º°—

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