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∑”„À⇴≈≈åÀ¬ÿ¥°“√‡®√‘≠·≈–°“√·∫àßμ—«„π«ß®√‡´≈≈å √—°…“‚√§μà“ß Ê Õ¬à“ß¡“°¡“¬ ´÷Ëß “¡“√∂π”¡“®¥

(Cell cycle arrest) πÕ°®“°π’Ȭ—ß∑”„À⇴≈≈å쓬 ‘∑∏‘∫—μ√ ºŸâ‡¢’¬π∫∑§«“¡π’È®÷ß∑”°“√∑∫∑«π
·∫∫Õ–æÕæ‚∑´’ (Apoptosis) Õ’°¥â«¬ ß“π«‘®—¬π’È «√√≥°√√¡∑’ˇ°’ˬ«¢âÕß·≈–‡¢’¬π∫∑§«“¡π’È¢÷Èπ‡æ◊ËÕ
∑”„Àâ‡ÀÁ𧫓¡‡ªìπ‰ª‰¥â∑’Ë®–π” “√ °—¥®“°μâπøÑ“ √«∫√«¡¢âÕ¡Ÿ≈∑’ˇ°’ˬ«¢âÕ߉«â æ∫«à“¡’°“√‡ª≈’ˬπ

∑–≈“¬‚®√¡“„™â„π°“√√—°…“¡–‡√Áß∑àÕπÈ”¥’ ·μà ·ª≈ß‚§√ß √â“ß∑“߇§¡’¢Õß “√ Andrographolide
Õ¬à“߉√°Áμ“¡¬—ßμâÕß°“√°“√»÷°…“«‘®—¬‡æ‘Ë¡‡μ‘¡ „π ∑’Ëμ”·Àπàßμà“ß Ê „π‚§√ß √â“ß∑“߇§¡’ ∑”„À≥⇪ìπ
°“√»÷°…“„π —μ«å∑¥≈Õß ·≈–°“√∑¥≈Õß∑“ߧ≈‘π‘° Õπÿæ—π∏å∑’Ë¡’ƒ∑∏‘χ©æ“–¢÷Èπ Õ—π‰¥â·°à °“√μâ“π¡–‡√Áß

„π¡πÿ…¬åμàÕ‰ª ®÷ß®–¬◊π¬—π‰¥âÕ¬à“ß·∑â®√‘ß (Anticancer) ª°ªÑÕ߇´≈≈åª√– “∑ (Neuropro-
tective) μâ“π‰¢¡—π„π‡≈◊Õ¥º‘¥ª°μ‘·≈–μâ“π
*Suriyo T, Nanthanit P, Rangkadilok N,
Thiantanawat A, Watcharasit P, Satayavivad J. ÕÕ°´‘‡¥™—π (anti-dyslipidemic and antioxidant
Andrographis paniculata extracts and major con-
activities) μâ“π‰«√— (Antiviral) μâ“π°“√Õ—°‡ ∫
stituent diterpenoids inhibit growth of intrahe-
patic cholangiocarcinoma cells by inducing cell (Anti-inflammatory) πÕ°®“°π’Ȭ—ß»÷°…“ªØ‘°‘√‘¬“
cycle arrest and apoptosis. Planta Medica.
μàÕ°—π¢ÕßÕπÿæ—π∏å‡À≈à“π’È°—∫¬“ (Drug interaction)
2014;80:533-43.
·≈–¬—ß√«∫√«¡ƒ∑∏‘Ï·≈–«—μ∂ÿª√– ߧå∑’Ë„™â„π°“√®¥

‘∑∏‘∫—μ√¢Õß “√Õπÿæ—π∏å‡À≈à“π’ȉ«â ´÷Ëß®–‡ªìπ¢âÕ¡Ÿ≈
°“√∑∫∑«π«√√≥°√√¡¢Õß “√ Androgra-
”À√—∫ºŸâ π„®»÷°…“ “√ Andrographolide ·≈–
pholide ®“°μâπøÑ“∑–≈“¬‚®√·≈–Õπÿæ—π∏å¢Õß
Õπÿæ—π∏å¢Õß “√π’ÈμàÕ‰ª
“√π’È*
Aromdee C. Andrographolide: progression in its
©—π∑π“ Õ“√¡¬å¥’*
modifications and applications - a patent review
*§≥–‡¿ —™»“ μ√å ¡À“«‘∑¬“≈—¬¢Õπ·°àπ (2012-2014). Expert Opinion on Therapeutic
Patents. 2014;24(10):1129-38.
Expert Opinion on Therapeutic Patents. 2014;
24(10):1129-38.
ƒ∑∏‘Ïμâ“π‰«√— Chikungunya ¢Õß “√ Andro-
®“°°“√∑’ËμâπøÑ“∑–≈“¬‚®√ (Andrographis
grapholide „π‡´≈≈å‡æ“–‡≈’Ȭß*
paniculata) ‡ªìπæ◊™ ¡ÿπ‰æ√∑’Ë¡’°“√„™â∑“ß°“√·æ∑¬å
†
æ‘™≠“¿—§ «‘π∑–™—¬*, Parveen Kaur , Regina
„π·∂∫‡Õ‡™’¬¡“Õ¬à“߬“«π“πÀ≈“¬»μ«√√… ¡’°“√
†
Ching Hua Lee , Suwipa Ramphan *, Õμ‘™“μ‘
„™â„π°“√√—°…“ ·≈–¡’ƒ∑∏‘Ï∑“߇¿ —™«‘∑¬“¡“°¡“¬ ∑—Èß
,
°«¥°‘®°“√*, π‘μ«√“ «‘°—π*, »ÿ¢“∏‘¥“ Õÿ∫≈*****,
≈¥°“√Õ—°‡ ∫ μâ“πÕÕ°´‘‡¥™—π ª°ªÑÕßμ—∫ ª°ªÑÕß
‡
†
‘∑∏‘√—°…å √Õ¬μ√–°Ÿ≈ , Justin Jang Hann Chu ,
À—«„® ≈¥Õ“°“√∑âÕ߇ ’¬ °√–μÿâπ¿Ÿ¡‘§ÿâ¡°—π μâ“π‡™◊ÈÕ
,
Duncan R. Smith****
®ÿ≈‘π∑√’¬å μâ“π‰«√— μâ“π¡–‡√Áß ≈¥πÈ”μ“≈„π‡≈◊Õ¥
‡ªìπμâπ ‚¥¬ “√ ”§—≠„πμâπøÑ“∑–≈“¬‚®√ §◊Õ * ∂“∫—π™’««‘∑¬“»“ μ√å‚¡‡≈°ÿ≈ ¡À“«‘∑¬“≈—¬¡À‘¥≈
†
Andrographolide ∑”„Àâ “√π’È∂Ÿ°π”¡“„™â‡ªìπ·°π Yong Loo Lin School of Medicine, National
À≈—°„π°“√∑”Õπÿæ—π∏å¢Õß “√π’È„Àâ¡’ƒ∑∏‘Ï„π°“√ University of Singapore, Singapore.