Page 96 - วารสารกรมการแพทย์แผนไทยฯ ปีที่ 11 ฉบับที่ 3

Journal of Thai Traditional & Alternative Medicine Vol. 11 No. 3 September-December 2013 305

¢¡‘Èπ™—π (Curcuma longa) ‡ªìπ‡§√◊ËÕ߇∑» ¢π“¥ 200 ¡°./°°. ∑ÿ°«—π‡ªìπ‡«≈“ 3 ·≈– 20 —ª¥“Àå
·≈– ¡ÿπ‰æ√∑’Ë¡’ƒ∑∏‘Ï√—°…“·≈–∫√√‡∑“Õ“°“√¢Õß ®“°°“√»÷°…“æ∫«à“ “√‡§Õ√姟¡‘π “¡“√∂≈¥Õ—μ√“

‚√§μà“ßÊ ‰¥âÀ≈“¬™π‘¥ ‚¥¬¡’ “√ ”§Ì≠ §◊Õ “√ °“√‡°‘¥¡–‡√Áß°√–‡æ“–Õ“À“√‰¥â 40-50% ¥â«¬°“√
‡§Õ√姟¡‘π (curcumin) ‰¥â¡’√“¬ß“π®”π«π¡“°∑’Ë ≈¥· ¥ßÕÕ°¢Õß phospho-IκBα ·≈– 8-OHdG
∫àß™’È«à“ “√‡§Õ√姟¡‘π ¡’ƒ∑∏‘Ïμâ“π‡´≈≈å¡–‡√Áß ‚¥¬∑—Èß (phospho-IκBα and 8-OHdG expressions) ´÷Ëß

¬—∫¬—È߬’π∑’Ë∑”„À⇰‘¥¡–‡√Áß ¬—∫¬—Èß°“√·∫àßμ—«¢¬“¬ —¡æ—π∏å°—∫°“√°àÕ¡–‡√Áß°√–‡æ“–Õ“À“√ °“√«‘®—¬π’È™’È
®”π«π‡´≈≈å¡–‡√Áß ·≈–∑”„À⇴≈≈å¡–‡√Áß쓬·∫∫ „Àâ‡ÀÁπ«à“°“√‰¥â√—∫ “√‡§Õ√姟¡‘π„π√–¬–‡√‘Ë¡μâπ¢Õß
Õ–æÕæ‚∑´’ (Apoptosis) ∑—Èß„πÀ≈Õ¥∑¥≈Õß·≈– °“√‡°‘¥¡–‡√Áß°√–‡æ“–Õ“À“√ “¡“√∂≈¥Õ—μ√“°“√

„π —μ«å∑¥≈Õß ºŸâ«‘®—¬®÷ß∑”°“√»÷°…“º≈¢Õß “√ ‡°‘¥‚√§¡–‡√Áß™π‘¥π’ȉ¥â„πÀπŸ·√∑
‡§Õ√姟¡‘πμàÕ‚√§¡–‡√Áß°√–‡æ“–Õ“À“√„πÀπŸ·√∑
*Kawiya Sintara, Duangporn Thong-Ngam,
‚¥¬∑”„ÀâÀπŸ·√∑‡ªìπ¡–‡√Áß°√–‡æ“–Õ“À“√¥â«¬ “√
Suthiluk Patumraj, and Naruemon Klaikeaw.
‡ÕÁπ-‡¡∑‘≈-‡ÕÁπ-‰π‚∑√‚´¬Ÿ‡√’¬ (N-methyl-N- (2012) Curcumin Attenuates Gastric Cancer In-
duced by N-Methyl-N-Nitrosourea and Saturated
nitrosourea) ·≈– “√≈–≈“¬‡°≈◊Õ·°ßÕ‘Ë¡μ—« (satu-
Sodium Chloride in Rats. Journal of Biomedicine
rated sodium chloride) ‚¥¬„Àâ “√‡§Õ√姟¡‘π„π and Biotechnology. 2012: 915380.