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«—®—¬π’È ®÷߇ªìπ°“√æ‘ Ÿ®πå¬◊π¬—π √√æ§ÿ≥¢Õßμ”√—∫ ®”‡ ◊ËÕ¡·≈– ¡Õ߇ ◊ËÕ¡„π‚¡‡¥≈ÀπŸ·√∑∑’Ë∑”„À⇰‘¥

‡∫≠®¡Ÿ≈„À≠à„π —μ«å∑¥≈Õß«à“¡’ƒ∑∏‘Ï≈¥‰¢â ·°âª«¥ ‚√§Õ—≈‰´‡¡Õ√å (Alzheimerûs disease) ¥â«¬ “√
·≈–·°âÕ—°‡ ∫‰¥â ‡Õ∑‘≈§Õ≈‘π Õ´‘√‘¥‘‡π’¬¡ Õ‘ÕÕπ (ethylcholine
aziridinium ion; AF64A) ´÷Ëߺ≈°“√»÷°…“æ∫«à“
*Chayanin Kiratipaiboon, Rawiwan Manohan,
“√ °—¥‡Õ∑“πÕ≈®“°μâπæ√¡¡‘¢π“¥ 20, 40, 80
Chanida Palanuvej, Nijsiri Ruangrungsi and
¡‘≈‘°√—¡/°‘‚≈°√—¡πÈ”Àπ—°μ—« „Àâ∑“ߪ“° ‡ªìπ‡«≈“ 2
Pasarapa Towiwat. (2012) Antinociceptive and
anti-inflammatory effects of Ben-Cha-Moon-Yai —ª¥“Àå°àÕπ„Àâ “√‡Õ∑‘≈§Õ≈‘π Õ´‘√‘‡¥’¬¡ Õ‘ÕÕπ ‡¢â“
remedy. Journal of Health Research. 26(5): 277-
∑“ß‚æ√ß ¡Õß (Intracerebro-ventricular admin-
284.
istration) ·≈– 1 —ª¥“ÀåÀ≈—ß„Àâ “√¥—ß°≈à“« æ∫«à“

ÀπŸ·√∑∑’Ë∂Ÿ°∑”„À⇪ìπ‚√§Õ—≈‰´‡¡Õ√å ¡’§«“¡®”¥’¢÷Èπ
ƒ∑∏‘Ï¢Õßμâπæ√¡¡‘ (Bacopa monnieri) „π°“√
®”π«π‡´≈≈åª√– “∑∑’Ë∂Ÿ°∑”≈“¬‚¥¬ “√‡Õ∑‘≈§Õ≈‘π
‡æ‘Ë¡§«“¡®”·≈–ª°ªÑÕß ¡Õß„π‚¡‡¥≈‚√§Õ—≈
Õ´‘√‘‡¥’¬¡ Õ‘ÕÕπ °Á≈¥πâÕ¬≈ßÕ¬à“ß¡’π—¬ ”§—≠ · ¥ß
‰´‡¡Õ√å„π —μ«å∑¥≈Õß*
„Àâ‡ÀÁπ«à“ “√ °—¥‡Õ∑“πÕ≈®“°μâπæ√¡¡‘ “¡“√∂
πßπÿ™ ‡Õ◊ÈÕ∫—≥±‘μ*, ®‘πμπ“¿√≥å «—≤π∏√*, ÿ¿“æ√
‡æ‘Ë¡§«“¡®”·≈–ª°ªÑÕß ¡Õß®“°‚√§Õ—≈‰´‡¡Õ√剥â
¡—™¨‘¡–ªÿ√–*, °√°π° Ցߧπ‘π—π∑å**
„π —μ«å∑¥≈Õß ¥—ßπ—Èπμâπæ√¡¡‘®÷ß¡’»—°¬¿“æ∑’Ë®–
*¿“§«‘™“ √’√«‘∑¬“ §≥–·æ∑¬»“ μ√å ¡À“«‘∑¬“≈—¬
π”¡“»÷°…“·≈–æ—≤π“μàÕ‡π◊ËÕ߇æ◊ËÕ»÷°…“∂÷߃∑∏‘Ï
¢Õπ·°àπ
·≈–°≈‰°°“√ÕÕ°ƒ∑∏‘Ï„π°“√√—°…“‚√§ ¡Õ߇ ◊ËÕ¡
**¿“§«‘™“‡¿ —™‡§¡’·≈–‡¿ —™‡«∑ §≥–‡¿ —™»“ μ√å
¡À“«‘∑¬“≈—¬π‡√»«√ Õ—≈‰´‡¡Õ√åμàÕ‰ª
Journal of Ethnopharmacology, 2554;127:26-31.
*Nongnut Uabundit, Jintanaporn Wattanathorn,
μâπæ√¡¡‘ (Bacopa monnieri (L.) Wettst)
Supaporn Mucimapura, Kornkanok Ingkaninan
‡ªìπæ◊™„π«ß»å Scrophulariaceae ¡’™◊ËÕÕ◊Ëπ«à“ º—°¡‘ (2010) Cognitive enhancement and neuropro-
tective effects of Bacopa monnieri in Alzheimerûs
´÷Ëß°“√„™âμâπæ√¡¡‘μ“¡°“√·æ∑¬åæ◊Èπ∫â“π·≈–°“√
disease model. Journal of Natural Medicine, 127:
·æ∑¬å·ºπ‰∑¬ ®–„™â‡ªìπ¬“¢—∫‚≈À‘μ ·°â‰¢â ¢—∫æ‘… 26-31.
√âÕπ ¢—∫‡ ¡À– ∫”√ÿß°”≈—ß ∫”√ÿßÀ—«„® ·≈–∫”√ÿß

ª√– “∑ ”À√—∫°“√„™âμ“¡Õ“¬ÿ√‡«∑¢ÕßÕ‘π‡¥’¬ ®– “√ °—¥πÈ”®“°μâπμ–‡§’¬πÀπŸ μâπ¡–‡§Á¥ μâπ¡–
„™â‡ªìπ¬“∫”√ÿߪ√– “∑ ∫”√ÿßÀ—«„® ¢—∫ªí “«– §—ß·¥ß μâπ‰¡¬√“∫ ·≈–√–¬àÕ¡πâÕ¬ ®“° ∞“π¢âÕ¡Ÿ≈
√—°…“‚√§≈¡™—° πÕπ‰¡àÀ≈—∫ ÀÕ∫À◊¥ ·≈–‚√§¢âÕ μ”√“¬“‰∑¬/≈â“ππ“ ¡‚π √âÕ¬ 2 (MANOSROI II) ¡’

Õ—°‡ ∫ ®“°°“√»÷°…“ƒ∑∏‘Ï¢Õß “√ °—¥®“°μâπæ√¡ ƒ∑∏‘Ï≈¥πÈ”μ“≈„π‡≈◊Õ¥„π —μ«å∑¥≈Õß*
¡‘„π —μ«å∑¥≈Õßæ∫«à“ ¡’ƒ∑∏‘Ï≈¥Õ“°“√«‘μ°°—ß«≈ ®’√‡¥™ ¡‚π √âÕ¬*, Zaruwa Z. Moses**, «√º°“